Lisseth had made her career as an actress. She had made her career in the films such as Chicago P.D, The OA, and The Fosters. She had made her roles in the Esperanza Spooner Cruz in the sixth and seventh seasons of the series such as Legends of Tomorrow. She holds the nationality of American. She had started her career in 2009. She had Salvadoran ancestry. She was nominated for the Latino Golden Globes award.
